NCCN Quick Guide™ | Neuroendocrine Tumors

1 of 2 NCCN QUICK GUIDE tm Neuroendocrine Tumors, 2018 This NCCNQUICK GUIDE tm sheet summarizes key points from the complete NCCN Guidelines for Patients ® : Neuroendocrine Tumors . Th ese guidelines explain which tests and treatments are recommended by experts in cancer. To view and download the guidelines, visit NCC N.or g/patients or, to order printed copies, visit What are the endocrine and neuroendocrine systems? The endocrine system is made up of glands in the body. These glands help make and release fluids or hormones. The neuroendocrine system controls how the brain, spinal cord, and nerves (nervous system) work with the endocrine system. 8 9 What should you know about neuroendocrine tumors? These tumors can be cancer (malignant) or not cancer (benign). They occur in the endocrine system, which is spread throughout your body. 11 How do your doctor and you decide on a treatment plan? The results from the exam of your body, blood and urine tests, imaging tests, and in some cases a biopsy will determine your next steps of care. 23 What are possible treatment options for neuroendocrine tumors? „„ Surgery is a primary treatment for neuroendocrine tumors that have not spread or have only spread to a limited extent. 26 „„ Radiation therapy uses high-energy rays to treat cancer. There are different ways to give radiation. The method used depends on the type of tumor and the purpose of radiation. 31 „„ Hepatic-directed therapies are aimed to treat cancer in the liver. These therapies include different types of embolization, along with cytoreductive surgery, and ablation. 31 „„ Drugs can also be given to treat cancer throughout the body. This is called systemic therapy. Some of the systemic therapies for neuroendocrine tumors include chemotherapy, targeted therapy, and immunotherapy. 32 „„ Somatostatin analogs are drugs that are similar to the hormone somatostatin. Somatostatin analogs reduce the amount of hormone secreted from the functional tumors and help stabilize tumor growth. 34 „„ Radiopharmaceutical drugs may be used to treat certain types of neuroendocrine tumors that start in the middle of the GI ( g astro i ntestinal) tract. This type of drug includes a radioactive substance that gives off small amounts of radiation. 35 „„ Clinical trials are research studies that people choose to take part in. Clinical trials are an important option for people with neuroendocrine tumors. 36 NCCN Guidelines for Patients ® Page Number Ü NCCN GUIDELINES FOR PATIENTS ® NCCN QUICK GUIDE tm Neuroendocrine Tumors 2018